Adrian Celaya

About Me

I am currently a Ph.D. student in the Department of Computational and Applied Mathematics (CAAM) at Rice University in Houston, TX. I am co-advised by Dr. Beatrice Riviere and Dr. David Fuentes. My research focuses on developing novel techniques for 3D medical image segmentation. Previously, I served as the Information System Security Manager onboard the U.S. Navy aircraft carrier USS Carl Vinson. After leaving the Navy in August 2020, I became a research assistant in the Department of Imaging Physics at The University of Texas MD Anderson Cancer Center.

Research Interests

  • Optimization
  • Numerical linear algebra
  • Scientific computing
  • Biomedical image segmentation
  • Deep learning
  • Geophysical inversion for CO$_2$ monitoring

Current Research Topics

FMG-Net and W-Net Architectures


Accurate medical imaging segmentation is crucial for effective medical interventions, but convolutional neural networks (CNNs) still struggle with fine-scale features and image scale variations, particularly in complex tasks like the BraTS brain tumor segmentation challenge. To address these challenges, we propose two architectures, FMG-Net and W-Net, that incorporate geometric multigrid principles into CNNs. Our experiments on the BraTS 2020 dataset show that FMG-Net and W-Net outperform the commonly used U-Net in tumor subcomponent segmentation accuracy and training efficiency. The figure above shows sketches of the U-Net, FMG-Net, and W-Net architectures for different network detphs. More details and results are available here.

Weighted Normalized Boundary Loss

The Weighted Normalized Boundary Loss (WNBL) is a boundary-based loss for minimizing the Hausdorff distance for deep learning-based medical imaging segmentation. This novel loss function has more desirable numerical properties than current methods and weighting terms for class imbalance. The WNBL outperforms other losses when tested on the BraTS dataset using a standard 3D U-Net and the state-of-the-art nnUNet architecture.

The WNBL is given below: \begin{align*} \mathcal{L}_{wnbl} = 1 - \frac{\sum_{k = 1}^{C} w_k \sum_{i = 1}^{N} \left(D_{i}^{k}\left((1 - T_{i}^{k})^2 - P_{i}^{k}\right)\right)^2}{\sum_{k = 1}^{C} w_k \sum_{i = 1}^{N} \left(D_{i}^{k}\left((1 - T_{i}^{k})^2 - T_{i}^{k}\right)\right)^2}, \end{align*} where $N$ denotes the total number of pixels (or voxels in the 3D case), $C$ denotes the number of segmentation classes, $P_i^k \in [0, 1]$ is the $i$-th voxel in the $k$-th class of the predicted mask, $T_i^k \in \{0, 1\}$ is the $i$-th voxel in the $k$-th class for the ground truth, and $D_i^k \in \mathbb{R}$ is the $i$-th voxel for the $k$-th class in the ground truth distance transform map. More details and results are available here.

Deep Learning-Based Inversion of Surface Gravity For CO$_2$ Monitoring


CO$_2$ geological storage is a carbon capture and storage technology that captures CO$_2$ emissions from fixed sources like power plants and stores it in underground saline formations, making it a practical and near-term solution. However, long-term monitoring is necessary to ensure volume storage integrity. 4D gravity monitoring is an effective low-cost and environmentally friendly technique for monitoring geological storage sites. To predict subsurface CO$_2$ plumes, a deep learning approach was developed that outperforms traditional inversion methods, producing high-resolution 3D subsurface reconstructions in near real-time. The figure above highlights the results of two of our proposed approaches. More details and results can be found here.

Grants and Fellowships

National Defense Science and Engineering (NDSEG) Fellowship

Sponsor: Department of Defense (Air Force Office of Scientific Research)
Dates: September 2022 to May 2025
Media:

Loewenstern Fellowship

Sponsor: Rice University
Dates: August 2021 to October 2022

Publications and Presentations

Selected Publications

A. Celaya, B. Riviere, and D. Fuentes. "FMG-Net and W-Net: Multigrid Inspired Deep Learning Architectures For Medical Imaging Segmentation," submitted to 37th Conference on Neural Information Processing Systems, under review, 2023.
A. Celaya, A. Diaz, A. Balsells, B. Riviere, and D. Fuentes. "A Weighted Normalized Boundary Loss for Reducing the Hausdorff Distance in Medical Imaging Segmentation," submitted to 26th International Conference on Medical Image Computing and Computer Assisted Intervention, under review, 2023.
A. Celaya, B. Denel, Y. Sun, M. Araya-Polo, and A. Price. "Inversion of Time-Lapse Surface Gravity Data for Detection of 3D CO$_2$ Plumes via Deep Learning," in IEEE Transactions on Geosciences and Remote Sensing, doi: 10.1109/TGRS.2023.3273149.
R. Muthusivarajan, A. Celaya, J. Yung, S. Viswanath, D. Marcus, C. Chung, and D. Fuentes. "Evaluating the relationship between magnetic resonance image quality metrics and deep learning-based segmentation accuracy of brain tumors," submitted to Medical Physics, under review, 2022.
A. Celaya, J. A. Actor, R. Muthusivarajan, E. Gates, C. Chung, D. Schellingerhout, B. Riviere, and D. Fuentes. "PocketNet: A Smaller Neural Network For Medical Image Analysis," in IEEE Transactions on Medical Imaging, doi: 10.1109/TMI.2022.3224873.
E. Gates, D. Suki, A. Celaya, J. Weinberg, S. Prabhu, R. Sawaya, J. Huse, J. Long, D. Fuentes, and D. Schellingerhout. "Cellular Density in Adult Glioma, Estimated with MR Imaging Data and a Machine Learning Algorithm, Has Prognostic Power Approaching World Health Organization Histologic Grading in a Cohort of 1181 Patients," in American Journal of Neuroradiology, doi: 10.3174/ajnr.A7620.
E. Gates, A. Celaya, D. Suki, D. Schellingerhout, and D. Fuentes. "Technical Note: An efficient MR image data quality screening dashboard," in Journal of Applied Clinical Medical Physics, doi: 10.1002/acm2.13557.

Selected Presentations

A. Celaya. "Inversion of Time-Lapse Surface Gravity Data for Detection of 3D CO$_2$ Plumes via Deep Learning," in 16th Annual Energy High Performance Computing Conference. Technical Talk. Houston, TX. February 2023.
A. Celaya. "PocketNet: A Smaller Neural Network For Medical Image Analysis," in 5th Annual SIAM Texas-Louisiana Section Meeting. Invited Minisymposium Presentation. Houston, TX. November 2022.
A. Celaya. "Small Convolutional Neural Networks for Efficient 3D Medical Image Segmentation," in 63rd American Association of Physicists in Medicine Annual Meeting. Virtual. July 2021.

Software

Medical Imaging Segmentation Toolkit (MIST)

The software MIST is a simple, fully automated framework for deep learning-based medical image segmentation. The framework can seamlessly ingest various medical imaging data and is easily expandable to test new ideas (i.e., new architectures, loss functions, etc.). MIST is open source, written in Python for PyTorch and TensorFlow. Please star the MIST repository!

Contact Me

  • Houston, TX
  • aecelaya@rice.edu
  • aecelaya@mdanderson.org